The endocannabinoid system (ECS) helps the body maintain balance, regulate vital autonomic processes (from sleep and inflammation to immune responses and hunger) and is vital to overall health and function. It's a complex network of receptors and neurotransmitters that respond to cannabinoids, like those found in CBD products.
What Is the Endocannabinoid System?
The endocannabinoid system is a complex network of receptors that regulate physiological responses to specific chemical signals, ultimately enabling the entire body to maintain homeostasis.
It was discovered in 1992 when researchers identified the brain’s own version of tetrahydrocannabinol (THC). This discovery launched further research into how the body interacts with cannabinoids, and how it produces its own cannabinoids (known as endocannabinoids).
The endocannabinoid system is made up of two major components: the CB1 and CB2 receptors and the enzymes responsible for synthesizing and breaking down endocannabinoids. The CB1 receptor is primarily located in the central nervous system, while the CB2 receptor is found mostly in immune cells.
The two types of receptors respond differently to cannabinoids, which allow them to regulate various bodily processes like:
- Appetite
- Mood
- Pain sensation
- Inflammation
In addition to these two receptors, the endocannabinoid system also includes the enzymes responsible for producing and breaking down endocannabinoids. These enzymes are responsible for regulating the levels of cannabinoids in the body.
The Role of Cannabinoids in the Endocannabinoid System
The endocannabinoid system is a complex network of receptors located throughout the body and brain. These receptors interact with endogenous cannabinoids (endocannabinoids) that are produced naturally in the body. These endocannabinoids are responsible for modulating and maintaining balance in the body.
Cannabinoids, including both endocannabinoids and phytocannabinoids, affect the endocannabinoid system by binding to the receptors. Endocannabinoids are those produced within the body, while phytocannabinoids are those found in plants, like cannabis.
Phytocannabinoids, such as cannabidiol (CBD), can activate or block certain receptors depending on the concentration of the cannabinoids and the person’s tolerance. This interaction between CBD and the ECS generates predictable physiological responses. Using CBD may also stimulate the production of endocannabinoids and encourage their release into the body, helping maintain balance.
In addition to these effects, CBD can also directly interact with enzymes that are responsible for breaking down endocannabinoids. By inhibiting their activity, it allows endocannabinoids to remain in the body longer, enhancing their impact on various bodily functions.
What Does the Endocannabinoid System Regulate and How Does CBD Affect It?
CBD’s effect on the ECS can be seen in a variety of physiological and psychological reactions:
- Mood
- Memory
- Appetite
- Pain
- Immune response
CBD essentially mimics the body’s reaction to its own endocannabinoids by binding to specific receptors on cells, which then triggers various biological responses. This can be particularly valuable if for whatever reason your body isn’t generating an adequate natural endocannabinoid response without intervention. For example, CBD may act on the CB1 receptor to reduce inflammation and help manage pain. It can also bind to CB2 receptors to help regulate the immune system.
CBD is not psychoactive, meaning it does not cause any of the "high" effects associated with THC. Rather, CBD works with the body’s existing ECS to promote balance within the body. Regular CBD users often advocate for our products due to the life-improving benefits they experience with regular use, including improved sleep, reduced inflammation and better overall health.
If you have any more questions about CBD products and how they work within your body, we encourage you to refer to our FAQ.
Find Helpful CBD Products at Revana Collective
Revana Collective sells Oregon-grown CBD products. Our company values are centered on creating high-quality, lab-tested CBD topicals and tinctures and helping our customers live healthier, more balanced lives. You can learn more about us and our commitment to quality products by browsing through our website.
